Table 2.
Adverse Events Occurring More Than 10% and All-Grade 3 to 4 Adverse Events Possibly, Probably, or Definitely Related to Study Drugs Graded by CTCAE Version 4 (N = 10)
| Treatment-Related Adverse Event | All (%) | Grades 3–4 |
|---|---|---|
| Diarrhea | 9 (90) | 2 (20%) |
| Rash acneiform | 6 (60) | 0 |
| Lymphocyte count decreased | 5 (50) | 1 (10%) |
| Anorexia | 5 (50) | 1 (10%) |
| Fatigue | 4 (40) | 0 |
| Creatinine increased | 4 (40) | 0 |
| Anemia | 4 (40) | 0 |
| Nausea | 4 (40) | 0 |
| Hypoalbuminemia | 3 (30) | 0 |
| Weight loss | 3 (30) | 0 |
| Dry skin | 3 (30) | 0 |
| Hypokalemia | 3 (30 | 1 (10%) |
| Colitis | 2 (20) | 2 (20%) |
| Paronychia | 2 (20) | 0 |
| Headache | 2 (20) | 0 |
| Mucositis | 2 (20) | 0 |
| Pruritus | 2 (20) | 0 |
| Elevated liver function tests | 2 (20) | 0 |
| Vomiting | 2 (20) | 0 |