Figure 1.

Severe acute respiratory syndrome coronavirus 2–specific T-cell responses. Antigen-specific total (top) and central memory CD27⁺CD45RA^– (bottom) interferon-γ CD8⁺ (left) and CD4⁺ (right) T-cell responses in the cohort described in Table 1. Cellular immune responses are shown to WA1/2020 membrane, nucleocapsid, envelope, and spike as well as XBB.1.5 spike. Dotted lines reflect limit of detection. Abbreviations: CM, central memory; Env, envelope; IFN, interferon gamma; Mem, membrane; Nuc, nucleocapsid; S, spike.