TABLE 2.

Univariate and multivariate Cox regression analysis for overall survival of patients with bladder cancer (BLCA).

Variates	Univariate analysis		Multivariate analysis
	p value	HR (95% CI)	p value	HR (95% CI)
Gender (male vs. female)	0.796	1.175 (0.346–3.993)
Age (>65 vs. ≤65)	0.369	1.481 (0.628–3.488)
Tumor size (>5 cm vs. ≤5 cm)	0.012*	3.007 (1.276–7.086)	0.11	2.258 (0.832–6.124)
Tumor stage (≥T2 vs. ≤T1)	0.003*	9.272 (2.158–39.832)	0.049*	4.841 (1.007–23.286)
Tumor grade (High vs. low)	0.214	1.891 (0.692–5.173)
Vascular invasion (Yes vs. no)	0.005*	3.914 (1.494–10.253)	0.286	1.863 (0.594–5.847)
Lymph node metastasis (Yes vs. no)	0.535	1.339 (0.533–3.362)
Recurrence (Yes vs. no)	0.311	1.632 (0.632–4.213)
Distant metastasis (Yes vs. no)	0.041*	3.141 (1.045–9.438)	0.47	1.663 (0.418–6.609)
Surgical approach (partial vs. total cystectomy)	0.057	2.444 (0.973–6.136)
PGK1 expression (High vs. low)	0.007*	5.393 (1.586–18.345)	0.037*	3.768 (1.084–13.1)

Note: Statistical analyses were performed by Cox proportional hazards regression.

^* p value <0.05 was considered statistically significant.