Table 3.
Summary of results from the best model for entorhinal cortex and neurocognitive measures
Variables in best model | ADAS-Cog1I | MMSE | CERAD | |
---|---|---|---|---|
Estimate | Regression coefficient | Odds ratio | Odds ratio | |
Agea | Estimate | 0.03 | 0.96 | |
95% CI | 0.003, 0.06 | 0.92, 1.00 | ||
P-value | 0.03* | 0.04* | ||
ApoE e4b | Estimate | 0.46 | ||
95% CI | 0.11, 0.81 | |||
P-value | 0.01* | |||
Years of Educationa | Estimate | −0.05 | 1.11 | |
95% CI | −0.10, −0.01 | 1.03, 1.20 | ||
P-value | 0.02* | 0.005* | ||
Right Entorhinal Volumea | Estimate | 2.62 | ||
95% CI | 1.04, 6.57 | |||
P-value | 0.04* | |||
Right Entorhinal Na-SIa | Estimate | 0.94 | 0.23 | |
95% CI | 0.11, 1.77 | 0.09, 0.60 | ||
P-value | 0.03* | 0.003* | ||
Adjusted R squared | 15.14 | 10.32 | 5.85 | |
Akaike Information Criteria | 81.00 | 80.00 | 78.00 | |
Addition of cerebral amyloid status | ||||
Cerebral amyloid statusb | Estimate | 0.60 | 0.48 | 0.27 |
95% CI | 0.11, 1.09 | 0.27, 0.88 | 0.13, 0.57 | |
P-value | 0.02* | 0.02* | <0.001* | |
Cerebral amyloid statusc | Estimate | 0.27 | 1.03 | 0.55 |
95% CI | −0.05, 0.59 | 0.63, 1.68 | 0.31, 0.98 | |
P-value | 0.10 | 0.91 | 0.04* | |
Adjusted R squared | 20.56 | 13.03 | 13.81 | |
Akaike Information Criteria | 83.00 | 82.00 | 80.00 |
aLevel: x + 1, Baseline: x.
bLevel: Positive, Baseline: Negative.
cLevel: Unknown, Baseline: Negative.
* P < 0.05.