Table 4.
Summary of results from the best model for precuneus and neurocognitive measures
Variables in best model | ADAS-Cog11 | MMSE | CERAD | |
---|---|---|---|---|
Estimate | Regression coefficient | Odds ratio | Odds ratio | |
Sexa | Estimate | 1.68 | ||
95% CI | 1.09, 2.59 | |||
P-value | 0.02* | |||
ApoE e4b | Estimate | 0.35 | ||
95% CI | 0.01, 0.68 | |||
P-value | 0.04* | |||
Years of Educationc | Estimate | −0.05 | 1.09 | 1.11 |
95% CI | −0.09, −0.003 | 1.02, 1.17 | 1.03, 1.20 | |
P-value | 0.04* | 0.01* | 0.005* | |
Left Precuneus Na-SIc | Estimate | 8.40 | ||
95% CI | 3.51, 13.28 | |||
P-value | 0.001* | |||
Right Precuneus Na-SIc | Estimate | −9.39 | 1064 | |
95% CI | −14.85, −3.93 | 14.78, 76880 | ||
P-value | 0.001* | 0.001* | ||
Left Cuneus Na-SIc | Estimate | 0.01 | ||
95% CI | 0, 0.05 | |||
P-value | <0.001* | |||
Right Cuneus Na-SIc | Estimate | 2.51 | ||
95% CI | 0.68, 4.33 | |||
P-value | 0.008* | |||
Adjusted R squared | 22.13 | 14.81 | 5.85 | |
Akaike Information Criteria | 82.00 | 81.00 | 78.00 | |
Addition of cerebral amyloid status | ||||
Cerebral amyloid statusb | Estimate | 0.49 | 0.53 | 0.27 |
95% CI | 0.01, 0.97 | 0.29, 0.96 | 0.13, 0.57 | |
P-value | 0.045* | 0.035* | <0.001* | |
Cerebral amyloid statusd | Estimate | 0.18 | 1.07 | 0.55 |
95% CI | −0.13, 0.49 | 0.66, 1.76 | 0.31, 0.98 | |
P-value | 0.25 | 0.78 | 0.041* | |
Adjusted R squared | 24.73 | 16.64 | 13.81 | |
Akaike Information Criteria | 84.00 | 83.00 | 80.00 |
aLevel: Woman, Baseline: Man.
bLevel: Positive, Baseline: Negative.
cLevel: x + 1, Baseline: x.
dLevel: Unknown, Baseline: Negative.
* P < 0.05.