FIG. 5.
V3 region replacement during progression of the infection in ponies 564 and 567. The percentage of V3 amino acid variation from the EIAVPV inoculum was calculated for sequential viral isolates. Percentage of variation was calculated by dividing the number of alterations within the designated V3 region by the total number of amino acids in the inoculum EIAVPV V3 region. Amino acid substitution, insertions, and deletions were all included in the assessment of V3 domain variation during sequential disease cycles (I through VI) and after long-term asymptomatic infection (MΦ).