TABLE 2.
Neutralizability of consecutive virus samples obtained from cats infected with TCA FIV by consecutive sera from the same cats
| Serum
|
Neutralizing antibody titer with virus isolate obtained from:a
|
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cat 275 at indicated mo p.i.
|
Cat 311 at indicated mo p.i.
|
Cat 583 at indicated mo p.i.
|
||||||||||||
| Donor cat | Mo p.i. at collection | 1 | 3 | 6 | 10 | 15 | 10 | 15 | 1 | 3 | 6 | 10 | 15 | 20 |
| 275 | 1 | − | − | − | − | − | − | − | − | 8 | − | − | − | − |
| 3 | 181 | − | − | − | − | − | − | 181 | 512 | 512 | 45 | 32 | − | |
| 6 | >512 | 45 | − | − | − | − | − | >512 | >512 | >512 | 181 | 11 | − | |
| 10 | >512 | 76 | 8 | − | − | − | − | >512 | >512 | >512 | >512 | − | − | |
| 15 | >512 | 512 | 32 | 8 | − | − | − | >512 | >512 | >512 | >512 | 181 | − | |
| 311 | 1 | − | − | − | − | − | − | − | − | − | 11 | 11 | − | − |
| 3 | >512 | 11 | 11 | − | − | − | − | >512 | >512 | >512 | >512 | − | − | |
| 6 | >512 | >512 | 8 | − | − | − | − | >512 | >512 | >512 | >512 | − | − | |
| 10 | >512 | 181 | 45 | − | − | 11 | 11 | >512 | >512 | >512 | >512 | 11 | − | |
| 15 | >512 | 512 | 57 | − | − | 20 | − | >512 | >512 | >512 | >512 | 11 | − | |
| 583 | 1 | 8 | − | − | − | − | − | − | 128 | 38 | 11 | − | − | − |
| 3 | >512 | 11 | − | − | − | − | − | 512 | 181 | 181 | 64 | 11 | − | |
| 6 | 512 | − | − | − | − | − | − | 181 | >128 | 181 | 181 | − | − | |
| 10 | >512 | 8 | − | − | − | − | − | 512 | >128 | 181 | 181 | 11 | − | |
| 15 | >512 | − | − | − | − | − | − | 512 | >128 | 181 | 181 | − | − | |
a
Values shown are the geometric means of the titers obtained in two independent assays. −, no neutralizing activity detected; mean titers of <8 were not considered significant and were scored as negative.