Figure 1.

Patient 3 received 3 intratumoral injections of rV-B7.1 (4.26 × 10⁷ PFU) in a left inguinal subcutaneous melanoma lesion. Following the last vaccine she developed new autoimmune vitiligo involving the right lower chin (A) and a skin graft donor site on the right lateral thigh (B). She had a complete response of metastatic disease, and excision of the left inguinal melanoma revealed necrotic tumor. She has had no evidence of recurrent disease for more than 59 months.