Fig. 4.

Comparison of U251 and U87 cell gene expression when grown in vitro and in vivo as s.c. and i.c. tumors in SCID mice by using gedi analysis. Gene expression profiles generated for U251 and U87 cells grown in tissue culture (A), as s.c. xenografts (B), and as i.c. xenografts (C) were subjected to gedi analysis. Genes with similar expression levels were grouped within the same tile; the maroon tiles correspond to highly expressed genes, yellow tiles correspond to genes with intermediate expression, and dark blue tiles correspond to genes with the lowest expression.