| antiSMASH |
genome mining |
bacteria, fungus, archaea,
plant |
flagship genome
mining tool
for NPs; different flavors depending on the organism/biome of choice |
(27) |
| PRISM 4 |
genome mining |
bacteria |
emphasis on predicting chemical
structures of predicted BGC products |
(31) |
| EvoMining |
genome mining |
bacteria |
focus on overlooked enzyme
classes through an evolutionary lens |
(32) |
| GECCO |
genome mining |
bacteria |
uses a specific subset of
ML, conditional random field, which makes it more interpretable than
neural network “black box” tools |
(29) |
| SanntiS |
genome mining |
bacteria |
uses an artificial neural
network and aims to better identify less-characterized BGCs |
(30) |
| BiG-SLiCE |
phylogenetic analysis |
bacteria, archaea |
generates gene cluster families
from BGCs |
(33) |
| CORASON |
phylogenetic analysis |
bacteria |
shows evolutionary relationships
between BGCs within a gene cluster family using a multilocus phylogeny |
(34) |
| MIBiG |
repository |
bacteria,
archaea, fungi,
plants |
frequently
updated and validated
by subject matter experts |
(35) |
| antiSMASH-DB |
repository |
bacteria, archaea, fungi |
not as well curated as MIBiG;
depends on the quality of the antiSMASH analysis of a genome |
(36) |
