Figure 2.

Survival and response. (A) Overall change in PCI score from baseline after PIPAC for patients who had PCI results after at least two cycles of PIPAC, color-coded by RECIST response. Green bars represent those with progressive disease, burgundy bars represent partial response, and grey bars represent stable or no change. (B) Kaplan–Meier curves of overall survival and (C) progression-free survival, (D) Kaplan–Meier curves of overall survival and (E) progression-free survival stratified by baseline PCI scores, (F) histological images before PIPAC-OX treatment showing viable tumor cells with mucin with some fibrosis (PRGS 3), (G) histological images after PIPAC-OX treatment showing acellular mucin with some inflammatory response (PRGS 1). CI, confidence interval; NA, not available; OS, overall survival; OX, oxaliplatin; PCI, peritoneal cancer index; PFS, progression-free survival; PIPAC, pressurized intraperitoneal aerosolized chemotherapy; PRGS, peritoneal regression grading score.