Figure 2.

Injured p14 IVDs heal with restored disc height index (DHI) and biomechanical properties by d56 while injured p28 IVDs and adult IVDs do not

(A) digital X-rays used to calculate DHI in (B) p14, (C) p28, and (D) adult mice (biological n = 8–9/age) 56 days after injury. Scale bars represent 2.5 mm. (E) Representative loading curve for samples used to determine torsional (F and G) and (H–J) axial biomechanical parameters. Error bars = SD. Student’s t test with p < 0.05 determined significant differences between ctrl and inj for each age, depicted in graphs as a horizontal black line.