Table I.

Clinical parameters at each day post inoculation (pi) in pigs vaccinated (Montanide ISA 25, Montanide ISA 50, and Saponin groups) and unvaccinated (positive and negative control groups) against Streptococcus suis

GROUP	Parameter	1a	2	3	4	5	6	7	8	9	10	11	12	13
Positive control	Temperatureb	6.6%	53.3%	57.1%	27.3%	22.2%	40%	0%	0%	0%	0%	0%	0%	0%
n = 15	Respiratoryc	0.27	0.27	0.92	1.1	0.9	0.2	0.25	0.75	0	0.33	0	0	0.67
	CNSd	0	0.13	0.64	0.9	1	1	0	0	0	0	0	0	0
	Lamenesse	0.13	0.73	0.57	0.82	0.89	0.6	0.75	1	1	1.33	1.33	1	0.67
	Cumulative mortality	0%	0%	6.7%	26.7%	40%	66.7%	73.3%	73.3%	80%	80%	80%	80%	80%
Montanide ISA 25	Temperature	15.4%	0%	15.4%	15.4%	27.3%	12.5%	0%	0%	0%	0%	0%	0%	0%
n = 13	Respiratory	0.23	0.23	0.84	0.38	0.9	0.57	0.33	0.66	0.33	0.33	0.17	0.17	0.33
	CNS	0	0	0	0.85	0.81	0.43	0	0	0	0	0	0	0
	Lameness	0.23	0.53	0.23	0.54	0.54	0	0	0.17	0	0	0.17	0.17	0
	Cumulative mortality	0%	0%	0%	0%	15.4%	38.5%	53.8%	53.8%	53.8%	53.8%	53.8%	53.8%	53.8%
Montanide ISA 50	Temperature	12.5%	18.7%	12.5%	20%	7.7%	0%	8.3%	0%	0%	0%	0%	0%	0%
n = 16	Respiratory	0.37	0.62	0.75	0.8	0.45	0.5	0.5	0.36	0.1	0.27	0.18	0.18	0.36
	CNS	0	0.31	0.37	0.53	0.23	0	0.25	0	0	0	0	0	0
	Lameness	0.12	0.37	0.31	0.33	0.23	0	0.1	0.27	0	0	0.1	0	0
	Cumulative mortality	0%	0%	0%	6.2%	18.7%	25%	31.2%	31.2%	31.2%	31.2%	31.2%	31.2%	31.2%
Saponin	Temperature	0%	14.3%	7.1%	0%	15.4%	10%	0%	0%	11.1%	0%	0%	0%	0%
	Respiratory	0.14	0.14	0.14	0.46	0.38	0.55	0	0.22	0.11	0.12	0	0.12	0.12
	CNS	0	0	0.21	0	0.69	0	0	0	0.33	0	0	0	0
	Lameness	0	0.14	0.28	0.31	0.61	0.11	0.22	0.11	0.11	0.12	0.37	0.5	0.57
	Cumulative mortality	0%	0%	0%	7.1%	7.1%	35.7%	35.7%	35.7%	35.7%	42.8%	42.8%	42.8%	42.8%
Negative control	Temperature	12.5%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%
n = 8	Respiratory	0	0	0.25	0.25	0.25	0.37	0.25	0.25	0.25	0.37	0	0	0
	CNS	0	0	0	0	0	0	0	0	0	0	0	0	0
	Lameness	0	0	0	0	0	0	0	0	0	0	0	0	0
	Cumulative mortality	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%	0%

CNS — central nervous system

^aDays post inoculation

^bPercentage of pigs with greater than 41°C rectal temperature

^cMean respiratory score (0 = absence, 6 = severe)

^dMean central nervous system score (0 = absence, 3 = severe)

^eMean lameness score (0 = absence, 3 = severe)