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. Author manuscript; available in PMC: 2025 Aug 1.
Published in final edited form as: Birth Defects Res. 2024 Aug;116(8):e2393. doi: 10.1002/bdr2.2393

Table 4.

Diagnostic Metrics by Approach in HLHS Compared to Manual Clinical Review

C-CLOC Approach Broad Approach Exclusive Approach

True Positive 805 914 287
True Negative 137 0 212
False Positive 128 265 53
False Negative 109 0 627

Accuracy 79.9% 77.5% 42.3%
Sensitivity 88.1% 100.0% 31.4%
Specificity 51.7% 0% 80.0%

Accuracy was computed as % correctly classified (true positive + true negative)/total).