Table 5.
Kidney function parameters (mg/dL) of dams gavaged with 1% CMC (control), 1000 mg/kg BW/day CYA, or 1000 mg/kg BW/day MEL.
| Not pregnant | Pregnant | |||||
|---|---|---|---|---|---|---|
| Control | CYA | MEL | Control | CYA | MEL | |
| Blood urea nitrogen (mean ± SEM) | 17.18 ± 0.71 | 17.82 ± 2.33 | 62.45 ± 17.32^ | 14.72 ± 1.05 | 17.45 ± 2.26 | 78.25 ± 18.41^ |
| Creatinine (mean ± SEM) | 0.49 ± 0.02 | 0.59 ± 0.07 | 1.28 ± 0.27^ | 0.47 ± 0.01 | 0.59 ± 0.07 | 1.45 ± 0.22^ |
| Uric acid (mean ± SEM) | 3.57 ± 0.26 | 5.26 ± 0.27& | 4.18 ± 0.29 | 3.42 ± 0.24 | 3.37 ± 0.28 | 3.45 ± 0.12 |
Indicates significant difference from respective control and CYA group (p < 0.05).
Indicates significant difference from respective control and 10% MEL group (p < 0.05).