Table 5.
Odds ratios of gastric cancer and small intestinal cancer in patients with Lynch syndrome
| Variable | Adjusted odds ratio | 95% CI |
| Gastric cancer | ||
| Sex | ||
| Female | 0.4 | 0.14–1.18 |
| Male (ref) | 1 | |
| Race and ethnicity | ||
| Racial and ethnic minoritiesa | 0.84 | 0.28–2.51 |
| Non-Hispanic White (ref) | 1 | |
| Any family history of gastric cancer | ||
| Yes | 1.39 | 0.37–5.23 |
| No (ref) | 1 | |
| Helicobacter pylori infection | ||
| Yes | 5.52 | 1.72–17.75 |
| No (ref) | 1 | |
| Not tested | 0.29 | 0.05–1.52 |
| Small intestinal cancer | ||
| Sex | ||
| Female | 0.15 | 0.04–0.56 |
| Male (ref) | 1 | |
| Race and ethnicity | ||
| Racial and ethnic minoritiesa | 0.56 | 0.17–1.84 |
| Non-Hispanic White (ref) | 1 |
Multivariable logistic regression analysis adjusted for sex, race and ethnicity, MMR gene, family history of gastric cancer, and history of H. pylori infection for gastric cancer and adjusted for sex, race and ethnicity, and MMR gene for small intestinal cancer.
CI, confidence interval; MMR, mismatch repair.
a
Included people who were Asian, Black, or Hispanic.