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a, A DNAzyme-enabled AND gate29. b, A CRISPR-Cas9 system91. c, A logic-gated DNA nanorobot that conditionally releases payload molecules19,31. d, A combination of riboregulators and recombinases104. Based on these principles, other kinds of logic gates (OR, XOR, NOR and so on) and logic-gated cascades can be readily implemented as well.
