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. 2005 Mar 23;2(2):191–199. doi: 10.1093/ecam/neh077

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© The Author (2005). Published by Oxford University Press. All rights reserved.

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Application of Juzen-taiho-to, Hochu-ekki-to, Shofu-san, Oren-gedoku-to and prednisolone initiates histological changes in ear tissues of NC/Nga mice treated repeatedly with mite antigen. Mouse ears were separated 24 h after the fifth antigen application. Tissue sections were stained with hematoxylin–eosin. (A) no antigen; (B) control; (C) Juzen-taiho-to 100 mg/kg; (D) Juzen-taiho-to 300 mg/kg; (E) Hochu-ekki-to 100 mg/kg; (F) Hochu-ekki-to 300 mg/kg; (G) Shofu-san 100 mg/kg; (H) Shofu-san 300 mg/kg; (I) Oren-gedoku-to 100 mg/kg; (J) Oren-gedoku-to 300 mg/kg; (K) prednisolone 3 mg/kg.