Skip to main content
. 2024 Sep 7;10(18):e37536. doi: 10.1016/j.heliyon.2024.e37536

Table 1.

Potential Mycobacterium tuberculosis adhesins proteins analysed for incorporation into the fusion construct [22].

Adhesin Rv Number Host Receptor Reference
Alanine proline-rich antigen (Apa) Rv1860 Macrophages [29]
19-kDa Antigen (lpqH) Rv3763 Monocytes and macrophages [30]
Antigen 85 complex (Ag85) Rv0129c, Rv1886c, Fibronectin and elastin [31]
Rv3803c, and Rv3804c
Cpn60.2 molecular chaperone (Cpn60.2) Rv0440 CD43 on Macrophages [32]
Curli pili (MTP) Rv3312A Laminin, macrophages and epithelial cells [33]
Early secreted antigen (ESAT-6) Rv3874/Rv3875 Laminin [34]
Glutamine synthetase A1 Rv2220 Fibronectin [35]
Glyceraldehyde-3phosphate dehydrogenase (GAPDH) Rv1436 Fibronectin [36]
Heparin-binding hemagglutinin adhesin (HBHA) Rv0475 Epithelial cells [37]
L,D-transpeptidase Rv0309 Fibronectin and laminin [38]
Malate synthase (MS) Rv1837c Fibronectin, laminin, and epithelial cells [39]
Membrane protein Rv2599 Collagen, fibronectin and laminin [38]
Molecular chaperone DnaK (HSP70) Rv0350 Macrophages [32]
Mycobacterium cell entry-1 protein Rv0169 Epithelial cells [40]
N-acetylmuromoyl-L-alanine amidase Rv3717 Fibronectin and laminin [38]
PE-PGRS proteins Rv1759c, Rv1818c Fibronectin and macrophages [41]
PstS-1 (38-kDa antigen) Rv0934 Macrophages [30]
Type IV pili Rv3654c-Rv3660c Macrophage and epithelial cells [42]