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. 2024 Sep 7;10(18):e37536. doi: 10.1016/j.heliyon.2024.e37536

Table 4.

Predicted MHC I and MHC II Binding Epitopes on tnHSP70, lpqH, MTP and PstS1 using the IEDB

Adhesin Protein MHC I
MHC II
Allele Epitope Rank Allele Epitope Rank
tnHSP70 HLA-B∗40:01 REIAAHNKL 0.990 HLA-DRB3∗01:0 EVTFDIDANGIVHVT 0.11
HLA-A∗68:01 ETKGGVMTR 0.982 HLA-DRB3∗01:0 IEVTFDIDANGIVHV 0.13
HLA-B∗07:02 APRGIPQIEV 0.915 HLA-DRB3∗02:0 TRLIERNTTIPTKRS 0.08
HLA-A∗03:01 RIQEGSGLSK 0.913 HLA-DRB3∗01:0 QIEVTFDIDANGIVH 0.13
HLA-A∗02:03 RLIERNTTI 0.900 HLA-DRB5∗01:0 ANGIVHVTAKDKGTG 0.13



lpqH HLA-A∗11:01 ATKDGSHYK 0.960 HLA-DRB1∗03:01 ASGPKVVIDGKDQNV 2.50
HLA-A∗30:01 ATKDGSHYK 0.946 HLA-DRB1∗03:01 SGPKVVIDGKDQNVT 2.50
HLA-A∗26:01 NVNGVTLGY 0.928 HLA-DRB1∗03:01 AASGPKVVIDGKDQN 2.70
HLA-A∗03:01 ATKDGSHYK 0.872 HLA-DRB1∗03:01 GPKVVIDGKDQNVTG 2.70
HLA-A∗68:02 TTAAGNVNI 0.815 HLA-DRB1∗03:01 PKVVIDGKDQNVTGS 2.70



PstS1 HLA-B∗57:01 QTLQAFLHW 0.996 HLA-DRB5∗01:01 INYEYAIVNNRQKDA 0.60
HLA-B∗58:01 QTLQAFLHW 0.993 HLA-DRB5∗01:01 IINYEYAIVNNRQKD 0.66
HLA-B∗57:01 LSKQDPEGW 0.980 HLA-DRB5∗01:01 NYEYAIVNNRQKDAA 0.66
HLA-B∗07:02 TPASSPVTL 0.978 HLA-DRB5∗01:01 PIINYEYAIVNNRQK 0.66
HLA-B∗58:01 LSKQDPEGW 0.975 HLA-DRB5∗01:01 YEYAIVNNRQKDAAT 0.71



MTP HLA-B∗57:01 QTAPVPDYYW 0.994 HLA-DRB3∗01:01 APVPDYYWCPGQPFD 5.80
HLA-B∗58:01 QTAPVPDYYW 0.990 HLA-DRB3∗01:01 PVPDYYWCPGQPFDP 5.90
HLA-A∗01:01 QTAPVPDYY 0.977 HLA-DRB3∗01:01 VPDYYWCPGQPFDPA 6.00
HLA-A∗26:01 QTAPVPDYY 0.827 HLA-DRB3∗01:01 PDYYWCPGQPFDPAW 6.20
HLA-A∗30:02 QTAPVPDYY 0.805 HLA-DRB3∗01:01 TAPVPDYYWCPGQPF 6.80