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. 2024 Sep 25;25(6):bbae471. doi: 10.1093/bib/bbae471

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© The Author(s) 2024. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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CDHu40 genes identified. (A) Overlap of CDHu40 and other marker gene sets in the literature. The left bar shows that marker genes were either down- or up- regulated in NEPC samples as we identified. Genes marked by asterisks were absent from all other published marker genes compared here. (B) qPRC validation on 17 selected marker genes in three PCa cell lines, LNCaP, NCI-H660, and KUCaP13. (C) Validation of gene expression changes (log2FC) by newly published RNA-seq tumor samples with AR and NE features, including both AR+ and AR− samples. (D) Expression profile of CDHu40 genes obtained by different data sets.