Fig. 6.

Depicts the lifecycle of the malaria parasite Plasmodium within the human host and its interaction with bioactive compounds. [A] shows the chemical structures and formulas of cynaropicrin (C₁₉H₂₂O6), suggesting potential targets for therapeutic interventions. where [B] depicts the sequential stages of Plasmodium infection and propagation: sporozoites transmitted by the mosquito enter the liver cells where they mature into merozoites. These merozoites are then released into the bloodstream, infecting red blood cells and progressing through several stages, including the ring form, trophozoites, and schizonts, before culminating in gametocyte production. These gametocytes are taken up by another mosquito to complete the transmission cycle.