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. Author manuscript; available in PMC: 2024 Sep 25.
Published in final edited form as: Cancer. 2023 Nov 29;130(7):1052–1060. doi: 10.1002/cncr.35136

Table 3.

Number needed to treat with cALND to determine abemaciclib candidacy among females with HR+HER2- non-metastatic invasive breast cancer and 1–3 positive sentinel lymph nodes without high-risk features who underwent upfront surgery and completion axillary lymph node dissection.

Total number of positive LNs after cALND [n (row %)] Number Needed to Treat [n (95% CI)]
Overall 1–3 ≥4
Number of positive SLNs Overall 1,762 1,456 (82.6) 306 (17.4)
1 1,159 1,048 (90.4) 111 (9.6) 11 (9, 13)
2 419 317 (75.7) 102 (24.3) 5 (4, 5)
3 184 91 (49.5) 93 (50.5) 2 (2, 3)

Abbreviations: cALND: completion axillary lymph node dissection; CI: confidence interval; SLN: sentinel lymph node; LN: total lymph nodes