Figure 2.

Graphical representation of wild type NUP98 and its fusion partner structures, which involve functional domains for each fusion partner. BAH, bromo‐adjacent homology; DBD, DNA binding domain; GBD, Gle2‐binding domain; HMG, high mobility group; LBD, ligand‐binding domain; NLS, nuclear localization signal; OM‐LZ, octapeptide motif‐leucine‐zipper; PWWP, Pro‐Trp‐Trp‐Pro; Q‐rich, glutamine‐rich; RNB, RNA‐binding domain. Functional domains for VRK1, LOC348801 (LNP1), FN1, and ANKRD28 have not been identified so far.