Table 2.
Results of the mendelian randomization analysis.
| Exposures | Outcome | Method | MR | p | Heterogeneity | Pleiotropy | p | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| beta | SE | OR (95%CI) | Q | p | Intercept | SE | |||||
| Basophil count | CAD | MR egger | −0.063 | 0.110 | 0.94 (0.72–1.16) | 0.576 | 43.815 | 0.002 | −0.001 | 0.006 | 0.856 |
| Weighted median | −0.052 | 0.043 | 0.95 (0.86–1.03) | 0.230 | |||||||
| IVW | −0.081 | 0.041 | 0.92 (0.84–1.00) | 0.048 | 43.890 | 0.002 | |||||
| Eosinophil petcentage | CAD | IVW | −0.022 | 0.149 | 0.98 (0.69–1.27) | 0.881 | 488.451 | <0.05 | |||
| Monocyte count | CAD | MR egger | 0.005 | 0.034 | 1.00 (0.94–1.07) | 0.888 | 9.943 | 0.446 | −0.004 | 0.005 | 0.433 |
| Weighted median | −0.006 | 0.017 | 0.99 (0.96–1.03) | 0.725 | |||||||
| IVW | −0.021 | 0.012 | 0.98 (0.96–1.00) | 0.072 | 10.610 | 0.477 | |||||
| Neutrophil count | CAD | MR egger | 0.058 | 0.096 | 1.06 (0.87–1.25) | 0.546 | 67.531 | <0.05 | −0.001 | 0.006 | 0.846 |
| Weighted median | 0.053 | 0.036 | 1.05 (0.99–1.12) | 0.133 | |||||||
| IVW | 0.041 | 0.033 | 1.04 (0.98–1.11) | 0.216 | 67.617 | <0.05 | |||||
| C-reactive protein | CAD | MR egger | −0.407 | 0.141 | 0.67 (0.39–0.94) | 0.008 | 178.849 | <0.05 | 0.025 | 0.012 | 0.053 |
| Weighted median | −0.096 | 0.051 | 0.91 (0.81–1.01) | 0.058 | |||||||
| IVW | −0.141 | 0.069 | 0.87 (0.73–1.00) | 0.040 | 212.759 | <0.05 | |||||
| Lymphocyte count | CAD | MR egger | 0.007 | 0.071 | 1.01 (0.87–1.15) | 0.924 | 1,074.044 | <0.05 | 0.003 | 0.002 | 0.168 |
| Weighted median | 0.031 | 0.029 | 1.03 (0.98–1.09) | 0.285 | |||||||
| IVW | 0.095 | 0.030 | 1.10 (1.04–1.16) | 0.001 | 1,081.179 | <0.05 | |||||
CAD, coronary artery disease; SE standard error.