TABLE 2.
Results of hematology, biochemistry, and urinalysis in 11 horses with systemic leptospirosis.
| Variable | No. of horses with data | Reference range | Survivors median (range), N = 7 | Nonsurvivors median (range), N = 4 | All horses median (range), N = 11 |
|---|---|---|---|---|---|
| Hematology | |||||
| Hematocrit (%) | 11 | 30‐47 | 28.6 (23.6‐38) | 26 (19.6‐35) | 29 (19.6‐38) |
| Hemoglobin (g/dL) | 11 | 10.7‐16.5 | 11.1 (9.9‐14.3) | 8.9 (8.7‐13) | 10.9 (8.7‐14.3) |
| RBC (106/μL) | 10 | 6.4‐10.4 | 6.8 (5.87‐9.06) | 7.1 (6.91‐7.59) | 7.0 (5.87‐9.06) |
| WBC (103/μL) | 11 | 4.9‐11.1 | 7.3 (6.4‐10.06) | 11.2 (5.85‐26.9) | 7.3 (5.85‐26.9) |
| Neu (103/μL) | 10 | 2.5‐6.9 | 5.7 (3.2‐8.03) | 7.7 (5.36‐20.58) | 5.8 (3.2‐20.58) |
| PLT (103/μL) | 10 | 100‐250 | 122.5 (58‐174) | 46.5 (9‐83) | 90.5 (9‐174) |
| Biochemistry | |||||
| Creatinine (μmol/L) | 11 | 82‐147 | 580 (291‐1065) | 611 (171‐990) | 580 (171‐1065) |
| Urea (mmol/L) | 11 | 3.5‐7 | 18 (5.2‐34.1) | 16.4 (9.7‐36.5) | 18 (5.2‐36.5) |
| Bilirubin (μmol/L) | 10 | 9‐39 | 48 (30‐124.9) | 122.2 (45‐268) | 48 (30‐268) |
| GGT (IU/L) | 10 | 6‐31 | 15 (9.9‐23) | 19 (18‐20) | 16.5 (9.9‐23) |
| GDH (IU/L) | 10 | 0.5‐2.2 | 18.6 (6.5‐32.7) | 3 (1.2‐14.2) | 14.2 (1.2‐32.7) |
| SDH (IU/L) | 10 | 0.1‐7.6 | 11.4 (4.3‐18.7) | 6.2 (1‐11.5) | 8.8 (1‐18.7) |
| Albumin (g/L) | 10 | 22‐37 | 30 (26‐33) | 22 (21‐25) | 27 (21‐33) |
| Sodium (mmol/L) | 11 | 132‐146 | 129 (125.4‐137.9) | 116.7 (111.4‐120) | 129 (111.4‐137.9) |
| Potassium (mmol/L) | 11 | 2.4‐4.7 | 4.4 (3.3‐5.23) | 5.37 (3.1‐6.57) | 4.9 (3.1‐6.57) |
| Chloride (mmol/L) | 11 | 99‐109 | 94 (86‐111) | 82 (80‐92) | 92 (80‐104) |
| iCalcium (mmol/L) | 9 | 1.50‐1.75 | 1.59 (1.55‐1.98) | 1.29 (1.13‐1.68) | 1.58 (1.13‐1.98) |
| SAA (mg/L) | 11 | 0.5‐1.2 | 1893 (405‐4447) | 3795 (2223‐7865) | 3153 (405‐7865) |
| Fibrinogen (g/L) | 9 | 1.25‐2.85 | 3.6 (2.8‐5.3) | 3; 7.3 a | 3.6 (2.8‐7.3) |
| Urinalysis | |||||
| Specific gravity (g/L) | 10 | 1020‐1045 | 1009 (1005‐1018) | 1021 (1019‐1021) | 1005‐1021 |
| Protein, dipstick | 10 | <2+ | 1+ (0 to 3+) | 3+ (1+ to 3+) | 0 to 3+ |
| Blood/Hgb, dipstick | 10 | Negative | 4+ (1+ to 5+) | 4+ (4+ to 5+) | 1+ to 5+ |
| RBC/HPF | 8 | <5 | 0‐4 to >250/HPF | 0‐4 to >250/HPF | 0‐4 to >250/HPF |
| WBC/HPF | 8 | <5 | 0‐4 to 4‐8 | 0‐4 to 4‐8 | 0‐4 to 4‐8 |
Abbreviations: GGT, γ‐glutamyltransferase; GDH, glutamate dehydrogenase; HPF, high power field; iCalcium, ionized calcium; Neu, neutrophils; PLT, platelets; RBC, red blood cells; SAA, serum amyloid A; SDH, sorbitol dehydrogenase; WBC, white blood cells.
a
Fibrinogen only available in 2 nonsurvivors.