Table 1. Summary statistics for SNP rs2866164 in German, French, and U.S. Caucasian LLI and controls.
Sample (no. of individuals) | Frequency of minor allele (G) | Pallele | Pgenotype | Odds ratio (Wald 95% CI) |
---|---|---|---|---|
Germans | ||||
LLI (1,033) | 0.269 | 0.34 | 0.13 | 1.18 (0.96-1.46) |
Centenarians (370) | 0.276 | 0.28 | 0.30 | 1.21 (0.93-1.58) |
Controls (540) | 0.253 | |||
French | ||||
LLI (559) | 0.253 | 0.54 | NA | NA |
Controls (552) | 0.264 | |||
U.S. Caucasians | ||||
LLI, sample 1 (175) | 0.260 | 0.039 | NA | NA |
Controls, sample 1 (183) | 0.331 | |||
LLI, sample 2 (244) | 0.252 | 0.029 | NA | NA |
Controls, sample 2 (231) | 0.316 |
Pallele, P value from a χ2 test (1 df) for allele frequency difference; Pgenotype, P value from a χ2 test (2 df) for genotype frequency difference; CI, confidence interval; NA, not available. Data of French and U.S. Caucasian samples are as reported by Geesaman et al. (5). The second sample of the U.S. Caucasians represents proactively matched LLI and controls. For the U.S. Caucasians, the minor allele frequency and P value were recalculated from the reported counts and differ slightly from those in the original publication.