FIG. 4.

Replication of HPIV3 in cells constitutively expressing 2–5A synthetase. Cells constitutively expressing a 69-kDa form of 2–5A synthetase (HT1080 2–5A syn) and control vector-transfected cells (HT1080-Vector or HT1080) were infected with HPIV3 at an MOI of 0.1. (A) syncytium formation at 24 h postinfection. (B) Production of progeny virions. Infectious virus release was measured by plaque assay in the culture medium at 24 h postinfection. The results are representative of three independent assays.