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. 2005 Jun 2;33(10):3176–3184. doi: 10.1093/nar/gki628

Figure 1.

Figure 1

Base pairing with the isoC–isoG non-natural pair. (A) IsoC and isoG form a three hydrogen bond pair. (B) An isoG tautomer is complementary to T in Watson–Crick pairing. 2′-Deoxy-5-methylisocytidine and 2′-deoxyisoguanosine were used in this work (R = CH3, R′ = 2′-deoxyribose).