Figure 2.

Identification of the binding domains on JAML and CAR. (A) Diagram of GST or Fc constructs containing truncated versions of the extracellular domains of CAR and JAML. SP, signal peptide. C, IgC loop. V, IgV loop. (B) Binding of JAML-Fc fusion proteins to immobilized GST chimeras of CAR determined as in Figure 1. Data represent mean ± SE of three independent experiments performed in duplicate (p < 0.01).