Figure 4.

Subclinical LV dysfunction in breast cancer patients 12 months post‐AC. Relative and absolute LV GLS were used to identify patients developing subclinical LV dysfunction at 12 months. The stepwise process included (1) relative decrease in LV GLS ≥10%. (2) Absolute LV GLS <16%. In this cohort, patients who exhibited ≥10% relative decrease in GLS to an absolute GLS <16% were older, had a higher incidence of hypertension, a lower T1 LV GLS and higher LV mass compared with those with a GLS ≥16%. AC, anthracycline; GLS, global longitudinal strain; LV, Left ventricular; TTE, transthoracic echocardiogram.