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. 2024 Aug 14;633(8031):848–855. doi: 10.1038/s41586-024-07808-z

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Extended Data Fig. 4 — a, Phylogeny showing the relationship across Mla genes from Ae. tauschii and barley. Resistance Gene Analogs (RGA) represent Ae. tauschii and Resistance Gene Homologs (RGH) represent barley cultivar Morex. The Ae. tauschii RGA gene sequences were derived from different accessions (Supplementary Table 10). RGA/RGH families 1, 2 and 3 are indicated in blue, red and green, respectively. The tree was constructed using the unweighted UPGMA algorithm. Bootstrap support values are shown based on 5,000 replicates. b, SrTA1662 (Sr66) and Sr33 display different race specificities. Reactions to Puccinia graminis f. sp. tritici isolates KE17c-21 (race TTKTF), IT16a-19 (TTRTF), and KE305b-17 (TTKSK) of transgenic SrTA1662 (Sr66) wheat lines and non-transgenic nulls (1 to 6) and wheat Sr gene introgression lines and controls (7 to 13). 1, Fielder null (DPRM0050); 2, Sr66 (DPRM0051); 3, Sr66 (DPRM0059); 4, Fielder null (DPRM0062); 5, Sr66 (DPRM0071); 6, Fielder null (DPRM0072); 7. Sr45 (RL5406); 8. Sr33 (RL5405); 9. Sr24 (LcSr24Ag); 10. Sr31 (Little Club/Agent (CI 13523)); 11. Sr39 (RL5711); 12. Sr33 (Chinese Spring); 13. cv. Morocco.