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Reduced contingency effects achieved by varying the percentage of CS-US pairing are insensitive to nifedipine treatment. (A) Experimental design (seven to eight mice/group). Mice were injected with vehicle (open circles) or nifedipine (40 mg/kg, filled circles) and subjected to either a 10%, 50%, or 100% contingent acquisition procedure (see Materials and Methods for details). (B) Freezing 1 d after acquisition during a 2-min acclimation period (Pre-CS) and two test CSs.
