Fig. 6.

Activation of CTSB restrains the malignant biological behavior of retinoblastoma cells. A: The expression of Bcl-2 and Caspase-3 was measured by Western blotting; B: The levels of CTSB, p-BRCA1, BRCA1, p-STAT3, STAT3 and STING1 were measured by Western blotting; C: The levels of LC3II/I, Beclin1 and p62 were measured by Western blotting; D: Western blotting was used to measure the levels of GPX4, FTH1, SLC7A11 and HO-1; E: The levels of P18, P21 and Cyclin D1 were measured by Western blotting; F: The content of MDA was measured by a kit; G: The concentrations of inflammatory factors were assessed by ELISA. ^*P < 0.05, ^**P < 0.01, ^***P < 0.001 vs. the RB group