Table 1.
Some otherwise undetected composite genes reported by Domain Teams
| N-terminal gene | C-terminal gene | Composite gene |
|---|---|---|
| Hl1549 (lolD) ABC_tran | Hl1548 (lolE) FtsX E> 100 | b0879 (macB) ABC_tran/FtsX |
| Lipoprotein releasing system ATP-binding protein lolD | Lipoprotein releasing system transmembrane protein lolC | Macrolide-specific ABC-type efflux carrier |
| H. influenzae | H. influenzae | E. coli |
| Hl0769 (ftsE) ABC_tran | Hl0770 (ftsX) FtsX E> 100 | b0879 (macB) ABC_tran/FtsX |
| Cell division ATP-binding protein ftsE* | Cell division protein ftsX homolog* | Macrolide-specific ABC-type efflux carrier |
| H. influenzae | H. influenzae | E. coli |
| Hl0291 HMA E=2.10−4 | Hl0290 HMA/E1-E2ATPase/Hydrolase | b0484 (copA) HMA/HMA/E1-E2ATPase/Hydrolase |
| Hypothetical protein | Probable cation-transporting ATPase | Copper-transporting P-type ATPase |
| H. influenzae | H. influenzae | E. coli |
| Hl0988 (leu2) Aconitase | Hl0989 (leuD) Aconitase_C E=0.83 | b1276 (acnA) Aconitase/Aconitase_C |
| 3-isopropylmalate dehydratase large subunit* | 3-isopropylmalate dehydratase small subunit* | Aconitate hydratase 1 |
| H. influenzae | H. influenzae | E. coli |
| b3577 DctQ E=2.4 | b3578 DctM/DedA | Hl0147 DctQ/DctM/DedA |
| Hypothetical protein* | Hypothetical protein* | Hypothetical protein |
| E. coli | E. coli | H. influenzae |
| b2678 (proW) BPD_transp_1 | b2679 (proX) OpuAC E> 100 | HP0818 BPD_transp_1/OpuAC |
| Glycine betaine/L-proline transport system permease* | Glycine betaine-binding periplasmic protein precursor* | Osmoprotection protein (prowx) |
| E. coli | E. coli | H. pylori |
Probable gene fusions between adjacent genes detected by Domain Teams after the comparison of the chromosomes of E. coli, H. influenzae, and H. pylori. Here are listed only the composite genes not reported in AllFuse and FusionDB. Note, however, that the fusion between the two components can be reported in FusionDB or AllFuse, based on evidence from other genomes (*). Each gene is identified by its ordered locus name, followed by its name (if any), followed by the Pfam domain(s) found in the protein they code for. The BLAST2 E-value between one of the components and the composite protein is also reported.