Fig. 6. Micromixers based on Dean flows. a| Geometry and 3D model of a periodic disturbance micromixer (PDM). 90 semicircular structures were fabricated in the chip to generate Dean flows for mixing lipids in ethanol and water. Reproduced from ref. 101 with permission from the American Chemical Society, copyright [2021]. b| Lipid/polymer hybrid nanoparticle production using the toroidal micromixer (TrM). Reproduced from ref. 127 with permission from Elsevier, copyright [2022]. c| Nanoprecipitation of lipid-polymeric NPs in an MHF-SAR integrated device. Reproduced from ref. 128 with permission from the American Chemical Society, copyright [2010]. d| Applications of lateral structure to laminar, serpentine zig-zag and split and recombine micromixers, respectively. Reproduced from ref. 123 with permission from Elsevier, copyright [2020].
