Table 1. Treatment of SID patients.
| Treatments before NIS start | |
|---|---|
| Treatment | No. of patientsa |
| Immunoglobulinsb | 952 (37.2%) |
| Immunosuppressants | 390 (15.3%) |
| Corticosteroids | 1,005 (39.3%) |
| Other | 512 (20.0%) |
| None | 690 (27.0%) |
| IVIG treatmentc | |
| Treatment duration (days) | 403 (157 – 921) |
| Number of applications per subject | 12.0 (6 – 28) |
| Annual number of applications | 12.8 (10.6 – 15) |
| Dose per kg body weight (g/kg) | 0.3 (0.3 – 0.4) |
| Speed of infusion (mL/kg/h) | 2.0 (1.4 – 2.7) |
| Initial speed of infusion (mL/kg/h) | 1.0 (0.9 – 1.3) |
| Maximum speed of infusion (mL/kg/h) | 2.4 (2.0 – 3.0) |
aPercentages are based on the SID patients who received at least 1 IVIG administration and for whom at least 1 post-administration assessment was available; N = 2,557. Multiple answers possible. bI.e., non-naïve patients (see text). cMedians are shown, with interquartile ranges in square brackets. SID = secondary immunodeficiency; NIS = large-scale non-interventional study.