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. 2024 Sep 11;10(18):e37593. doi: 10.1016/j.heliyon.2024.e37593

Table 3.

MIC (μg/mL) values of the hop leaf extracts against Gram-positive strains and the MIC (μg/ml) of the antibiotics tested alone and in presence of the lowest effective concentration of Hop Leaf Extract (HLE).

Strains HLE MIC (μg/mL) Antibiotic Antibiotic MIC (μg/mL) Antibiotic MIC (μg/ml) in presence of HLE (μg/mL) FIC Index Effect
E. faecium KSEG3 500 Vancomycin 256 128 (62.5) 0.62 Additive
E. faecium LSEF2 500 Florfenicol 128 64 (1) 0.5 Synergistic
S. aureus MU50 250 Oxacillin 256 128 (1) 0.5 Synergistic
S. aureus K1902 125 Erythromycin 256 128 (16) 0.5 Synergistic