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Expression levels of surface proteins in wild-type CD4+ thymocytes cocultured with wild-type or Aire-deficient mTECs. The expression of CD152 (A) or CD28 (B). Data are presented as mean ± s.d. (replicates n = 3). The differences were evaluated using Student t test (p values are indicated for each comparison when pertinent). (**) = statistical significance.
