Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Sep 25;33:09636897241281869. doi: 10.1177/09636897241281869

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 4. — Organoids maintain the genetic alteration present in the original tumor. (A) A cancer-related set of variants was detected in both organoids and primary tumors with the mutation type indicated in the legend. Gene variants in the tumor and organoid from the same patient exhibit identical. T: tumor, O: organoid. HGSC: high-grade serous carcinoma, CCC: clear cell carcinoma, MC: mucinous carcinoma. The preservation of genetic alteration from the original tumor is evident in organoids. (B) Stacked bar graphs depict the number of mutations per patient sample identified in cancer tissues and derived organoids, organoid only and tumor only. (C) The percentage of shared, organoid-only, and tumor-only. Primary tumors and organoids exhibited a shared variation percentage ranging from 22% to 59%.