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Middle-age presentation of ovarian and peritoneal tumors. A, Lifespan data from mice euthanized due to tumor burden criteria. B, Example of a dissected reproductive tract from a mouse with obvious macroscopic ovarian tumors. C, Examples of widespread intra-abdominal disease, including liver invasion (L), peritoneal tumors (P), splenic tumor (S), and ovarian tumors (Ov). L, liver invasion; Ov, ovarian tumors; P, peritoneal tumors; S, splenic tumor.
