Table 1.

Genome-wide association studies on HIV infection outcomes with top signals detected in the HLA locus.

Cohort	Outcome	Sample size	Reference
Euro-CHAVI	Set-point VL	486	[6]
	progression to CD4+ T-cell count <350 cells/μl	337
PRIMO (ANRS 01)	Early plasma HIV-RNA and cellular HIV-DNA level	605 unselected seroconverters	[4]
GRIV (ANRS 02)	AIDS nonprogression	275 slow progressors, 1352 seronegative controls	[9]
Euro-CHAVI	Set-point VL	2362	[5]
	progression to CD4+ T-cell count <350 cells/μl	1071
International HIV Controller Study	HIV-1 control	974 controllers, 2648 progressors	[10]
GRIV, MACS, ACS (low frequency SNPs only)	AIDS nonprogression	365 slow progressors, 1394 seronegative controls	[8]
GISHEAL, PRIMO	AIDS nonprogression	144 slow progressors, 605 unselected seroconverters	[7]

SNP, single nucleotide polymorphism; VL, viral load.