Fig. 7.

Differential gene expression analyses between livers with early allograft dysfunction (EAD, EAD1) and no early allograft dysfunction (=initial function (IF), EAD0). (a) Experimental design and number of livers for differential expression analyses and classification of EAD vs IF. (b) Heatmap of log2 fold changes (LOG2FC) and area under curve from receiver operating characteristics (AUC) at different time-points. (c) Visualization of AUC vs log2 fold changes (size of dots indicate p-values according to the legends and different time-points are indicated by colour intensity). (Test based on the negative binomial distribution using DESeq2).