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TABLE 1.

Inhibitory effects of E. coli-expressed IFN on FMDV replication

Cytokine Highest dilution that reduced FMDV plaque no. by 50% in:
EBK cells IBRS2 cells
Bovine IFN-α 1:8,100 1:3,200
Bovine IFN-β >1:8,100 a
Porcine IFN-α >1:8,100 >1:8,100
Porcine IFN-β 1:1,600 1:4,050
a

–, less than 1:100.