Table 1. Inclusion and exclusion criteria.

Inclusion Criteria	Exclusion Criteria
Age 18 years or older	Underwent ESS in past 12 months
Diagnosed with CF as established by genetic testing combined with clinical assessment and/or sweat chloride	Will obtain follow up care at nonparticipating institutions
Diagnosed with CRS by multidisciplinary sinusitis guidelines	Unable to complete outcome measures
CRS symptoms persisting beyond initial medical treatment	Started new CFTR modulator therapy less than 90 days prior to screening or anticipated to begin during study period

ESS, endoscopic sinus surgery; CF, cystic fibrosis; CRS, chronic rhinosinusitis, CFTR, cystic fibrosis transmembrane receptor