TABLE 1.
Transmission and in vitro binding efficiencies of CNV mutants
Virus | Transmissiona | % Bindingb |
---|---|---|
WT CNV | 49/51 (96) | 100.0 |
LLK00 | 10/10 (100) | 130.0 ± 8.5 |
LLK8 | 3/14 (21) | 68.3 ± 17.5 |
LLK10 | 4/15 (27) | 39.0 ± 22.3 |
LLK26 | 1/10 (10) | ND |
LLK63 | 3/21 (14) | 20.8 ± 17.2 |
LLK82 | 15/20 (75) | 64.3 ± 24.11 |
LLK84 | 10/20 (50) | 53.0 ± 7.5 |
LLK85 | 19/25 (76) | 53.0 ± 12.3 |
LL5K8 | 0/8 (0) | 21.7 ± 6.6 |
Number of pots showing transmission/number of pots tested. Values in parentheses indicate percentages of pots showing transmission. The data represent a compilation of at least three separate experiments for each virus.
Percentage of virus bound in an in vitro binding assay relative to the amount of WT CNV binding (average ± standard deviation of three separate experiments for each mutant). ND, not determined.