TABLE 1.

Characterization of primary virus cultures and recombinant soluble gp120 proteins^a

^aThe non-syncytium-inducing (NSI)/syncytium-inducing (SI) and R5/X4 phenotypes of the original PBMC-derived isolate in MT-2 and U87-CD4 coreceptor cells, respectively, are shown. All expressed gp120 proteins shown were able to bind the conformation-dependent MAb 58/30 and were tested for their ability to bind linear (12b) and conformation-dependent (697 and 55/39) anti-V2 MAbs, linear anti-V3 MAbs (268 and 257), 2G12, and sCD4-IgG. Also shown is the ability of clones derived from viral RNA to bind sCD4-IgG. A gp120 is considered to bind the respective ligand if its binding index relative to BH10 gp120 is greater than 0.2. NT, not tested. Data are presented as number positive/number tested.