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. 2024 Sep 13;15:1393137. doi: 10.3389/fendo.2024.1393137

Table 2.

Relationships of TP, ALB, and GLB with insulin resistance.

Odds ratio (95% CI), P-value
Model 1 Model 2 Model 3
TP (per 10g/L increment) 1.34 (1.26, 1.43) <0.0001 1.21 (1.13, 1.29) <0.0001 1.54 (1.41, 1.69) <0.0001
TP categories
 Q1 Reference Reference Reference
 Q2 1.29 (1.13, 1.46) <0.0001 1.21 (1.07, 1.38) 0.0032 1.28 (1.09, 1.50) 0.0025
 Q3 1.32 (1.17, 1.48) <0.0001 1.23 (1.09, 1.39) 0.0008 1.36 (1.17, 1.58) <0.0001
 Q4 1.51 (1.34, 1.70) <0.0001 1.38 (1.22, 1.55) <0.0001 1.53 (1.32, 1.77) <0.0001
 Q5 1.46 (1.31, 1.64) <0.0001 1.32 (1.17, 1.48) <0.0001 1.60 (1.39, 1.85) <0.0001
 Q6 1.65 (1.47, 1.84) <0.0001 1.40 (1.25, 1.58) <0.0001 2.06 (1.77, 2.40) <0.0001
 P for trend <0.0001 <0.0001 <0.0001
ALB (per 10g/L increment) 0.56 (0.51, 0.62) <0.0001 0.52 (0.47, 0.57) <0.0001 1.09 (0.95, 1.25) 0.1995
ALB categories
 Q1 Reference Reference Reference
 Q2 1.03 (0.91, 1.17) 0.6052 0.95 (0.84, 1.08) 0.4363 1.07 (0.91, 1.26) 0.3993
 Q3 0.90 (0.79, 1.03) 0.1345 0.81 (0.70, 0.92) 0.0021 1.09 (0.92, 1.30) 0.3117
 Q4 0.77 (0.69, 0.86) <0.0001 0.69 (0.62, 0.78) <0.0001 1.14 (0.98, 1.32) 0.0927
 Q5 0.72 (0.63, 0.82) <0.0001 0.64 (0.56, 0.74) <0.0001 1.14 (0.95, 1.36) 0.1544
 Q6 0.55 (0.49, 0.61) <0.0001 0.50 (0.44, 0.56) <0.0001 1.16 (0.99, 1.37) 0.0653
 P for trend <0.0001 <0.0001 0.062
GLB (per 10g/L increment) 2.08 (1.93, 2.24) <0.0001 1.93 (1.78, 2.10) <0.0001 1.62 (1.47, 1.79) <0.0001
GLB categories
 Q1 Reference Reference Reference
 Q2 1.26 (1.11, 1.44) 0.0004 1.26 (1.10, 1.43) 0.0006 1.19 (1.02, 1.40) 0.0275
 Q3 1.57 (1.39, 1.78) <0.0001 1.54 (1.36, 1.74) <0.0001 1.36 (1.17, 1.58) <0.0001
 Q4 1.84 (1.63, 2.08) <0.0001 1.78 (1.57, 2.02) <0.0001 1.45 (1.25, 1.69) <0.0001
 Q5 2.22 (1.95, 2.52) <0.0001 2.13 (1.86, 2.43) <0.0001 1.69 (1.44, 1.98) <0.0001
 Q6 2.77 (2.45, 3.12) <0.0001 2.54 (2.23, 2.88) <0.0001 1.91 (1.63, 2.23) <0.0001
 P for trend <0.0001 <0.0001 <0.0001

TP, total protein; ALB, albumin; GLB, Globulin.

Model 1: no adjustment; Model 2: adjusted for age, gender, and race; Model 3: adjusted for age, gender, race, education, systolic blood pressure, diastolic blood pressure, body mass index, smoking, diabetes, hypertension, coronary heart disease, acute myocardial infarction, chronic heart failure, stroke, cancer, alanine aminotransferase, aspartate aminotransferase, serum creatinine, glycated hemoglobin A1c, hemoglobin, total cholesterol, high-density lipoprotein cholesterol, triglycerides.