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. 2024 Sep 23;7(3):pbae018. doi: 10.1093/pcmedi/pbae018

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© The Author(s) 2024. Published by Oxford University Press on behalf of the West China School of Medicine & West China Hospital of Sichuan University.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 5. — Exosomal miR-30a-5p enhanced metastasis of cells in vivo. Representative images (A) and statistics (B) of lung metastasis nodules in mice intravenously injected with miR-30a-5p overexpression or control cells. (C) Lung weight of mice intravenously injected with miR-30a-5p overexpression or control cells. (D) Relative expression of miR-30a-5p in the metastatic nodules of different experimental groups. Representative images (E) and statistics (F) of lung metastasis nodules in mice intravenously injected with CNE-2 cells pre-treated with exosomes derived from miR-30a-5p overexpression or control cells. (G) Lung weight of mice intravenously injected with CNE-2 cells pre-treated with exosomes derived from miR-30a-5p overexpression or control cells. *, p<0.05; **, p<0.01; ***, p<0.001.