Table 2.
Development stage of clinical studies using bacteriophages registered on ClinicalTrials.gov on 15 August 2024 *.
| Status | Completed or Terminated | On Going or Not Yet Recruiting | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Phase | Pre-Clinical or Case Study | Phase | Pre-Clinical or Case Study | Phase | ||||||
| I | I/II | II | II/III | III | I/II | II | III | |||
| Staphylococcus aureus | 1 | 2 | 1 | 1 | 3 | 3 | 3 | |||
| Coagulase-negative Staphylococci | 1 | 3 | ||||||||
| Pseudomonas aeruginosa | 2 | 1 | 4 | 1 | 1 | 1 | 3 | 1 | ||
| Escherichia coli | 2 | 3 | 1 | 1 | 1 | 2 | 2 | 1 | 1 | |
| Enterococcus spp. | 1 | 1 | 1 | 2 | 1 | |||||
| Klebsiella | 1 | 1 | 1 | 1 | 1 | 2 | ||||
| Acinetobacter baumannii | 1 | 1 | 1 | 1 | ||||||
| Streptococcus | 1 | 1 | ||||||||
| Proteus | 1 | 1 | 1 | |||||||
| Non-tuberculosis Mycobacteria | 1 | 1 | ||||||||
| Achromobacter xylosoxidans | 1 | 1 | ||||||||
| Stenotrophomonas maltophilia | 1 | 1 | ||||||||
| Bacteroides fragilis | 1 | 1 | ||||||||
| Shigella | 1 | |||||||||
* Note: The numbers in the table represent the number of research projects (clinical trials). In some cases, phage cocktails targeting different bacteria are included, with each counted as one project. Most of the research projects are currently ongoing, so many have not yet been published. The table was compiled by the authors using the ClinicalTrials.gov database from the National Library of Medicine (https://clinicaltrials.gov/, accessed on 15 August 2024), and there are no comprehensive references for the entire table. It provides an overview of the current status of clinical studies using bacteriophages.